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Alphabetical listing of protein, pathway, and antibody acronyms, curated by Cell Signaling Technology.
Kinase-disease associations table showing kinases, kinase groups, disease types, and the molecular biology basis for disease.
Expert-reviewed diagram providing a current overview of the Mechanisms of Fibrosis pathway with references to its role in adhesion
Mutations in cell death pathways, such as apoptosis, mitophagy, necroptosis, and autophagy, contribute to neuronal cell death and the progression of neurodegenerative diseases.
Summary of human oncogenes and tumor suppressor genes sorted by signaling pathway.
When designing an antibody panel for multiplex IHC, it’s important to optimize each antibody’s dilution and which fluorophore it’s paired with. This will help your staining achieve a balanced set of signals.
A table that lists shelf-life expectations for CST products (when stored under the recommended conditions).
Phosphorylation and ubiquitylation events are of interest in preclinical investigations of cancer. This webinar considers study design for label-free mass spectroscopy analysis, enrichment strategies, and data analysis.
Expert-reviewed diagram providing a current overview of the m6A RNA pathway with references to its role in tumor development
Fostering mentorship, application-based learning, and a love of science are all part of the mission of the CST internship program. Students interning with us are partnered with CST Mentors.
Cellular senescence is characterized by irreversible cell-cycle arrest in combination with a distinct secretory phenotype and expanded lysosomes in response to stress. Senescent cells accumulate in tissues during aging, and various markers of senescence
Resources include signaling pathways, antibodies and companion products, research overviews, technical resources, and recent review articles.
The three main purposes of metabolism are the conversion of food to energy; the conversion of nutrients to proteins, carbohydrates, lipids, and nucleic acids; and the elimination of nitrogenous wastes. There is a strong correlation between metabolic chan
Uncovering the mechanisms underlying RNA modifications and RBP function are emerging frontiers in medicine that take the study of gene regulation a step beyond epigenetics
Understanding the underlying biology of fibrosis is critical for the diagnosis, treatment, and management of cardiac fibrosis, nonalcoholic steatohepatitis (NASH), and other fibrotic diseases
Epigenetic regulation, including aberrant DNA methylation and histone modifications, have been linked to Alzheimer’s disease, Huntington’s disease, Parkinson’s disease, multiple sclerosis, and amyotrophic lateral sclerosis.
Expert-reviewed diagram providing a current overview of the Senescence Signaling pathway with references to its role in cell cycle