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The Ubiquitin Ligase Table provides a comprehensive list of E3 ubiquitin ligases along with their substrates and corresponding PubMed reference(s).
Products and Related Resources for Type I Interferon and Viral Restriction Factors SARS-CoV-2 Research
Organelle markers for immunofluorescence analysis from CST Cell Signaling Technology
Products and Related Resources for Fibrosis SARS-CoV-2 Research
Products and Related Resources for Adaptive Immune Response SARS-CoV-2 Research
Products and Related Resources for Virus Detection and Innate Immune Activation SARS-CoV-2 Research
The Jak/Stat Utilization Table displays the combinatorial use of tyrosine kinases and Stat proteins in cytokine/growth factor signaling.
Products and Related Resources for Cytokines and Inflammation SARS-CoV-2 Research
The IFN-α (6B18) Mouse mAb #3110 and IFN-α (8C21) Mouse mAb #3115 antibodies are different clones to the same target. These antibodies are approved for use with recombinant protein and will not detect endogenous levels of IFN-α. While either antibody will work well, #3110 is slightly stronger than #3115 by western blot and in addition has some citations in CiteAb.
Angiogenesis, the formation of new blood vessels from pre-existing blood vessels, plays a key role in tumorigenesis.
Explore the complex inflammation signaling pathways. Click here to learn more and understand the molecular basis of inflammation.
Lymphoid lineage cells can be characterized using antibodies for cell type-specific markers, allowing cells to be visualized using flow cytometry or IHC.
This interactive guide shows the most important cell and functional state markers for tumor-infiltrating immune cells in mice.
The chromatin immunoprecipitation (ChIP) assay is a powerful and versatile technique to probe protein-DNA interactions within the natural chromatin context of the cell.
Expert-reviewed interactive pathway providing a current overview of the Inflammasome Signaling Pathway.
Expert-reviewed interactive diagram of Rheumatoid Arthritis Pathogenesis and relevant antibodies for studying targets associated with the autoimmune disease.
Given the limited but remarkable success of immune checkpoint blockade, recent efforts have been focused on identifying new targets for improving immunotherapy effectiveness in the immunosuppressive tumor microenvironment. One such target is T cell immunoreceptor with Ig and ITIM domains (TIGIT).
Cancer cells adapt mechanisms to evade death by hijacking mechanisms of immune checkpoint control and modulation of the innate immune response via STING.
New data suggests that ISG15 is a target of interest in the ongoing fight against COVID-19.
This interactive guide shows the key cell and functional state markers for tumor-infiltrating immune cells in humans.Web Location: Immunology and Inflammation
Alphabetical listing of protein, pathway, and antibody acronyms, curated by Cell Signaling Technology.
The immune system is composed of tissues, cells, and molecules whose primary function is to detect, respond to, and eliminate pathogens and transformed cells.
A comprehensive list of peer-reviewed publications from Cell Signaling Technology.
Streamline your oncology therapeutic development with CST recombinant monoclonal antibodies, ELISA and cellular assay kits, custom products, and services.
Kinase-disease associations table showing kinases, kinase groups, disease types, and the molecular biology basis for disease.
